MXI1 monoclonal antibody (M11), clone 1B10
产品名称： MXI1 monoclonal antibody (M11), clone 1B10
英文名称： MXI1 monoclonal antibody (M11), clone 1B10
产品编号： H00004601-M11
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full-length recombinant MXI1.
- Immunogen:
- MXI1 (AAH12907, 1 a.a. ~ 182 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (45.76 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to MXI1 on HeLa cell . [antibody concentration 10 ug/ml]
- Protocol Download
- Immunofluorescence
- Immunofluorescence of monoclonal antibody to MXI1 on U-2 OS cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged MXI1 is 0.03 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 4601
- GeneBank Accession#:
- BC012907
- Protein Accession#:
- AAH12907
- Gene Name:
- MXI1
- Gene Alias:
- MAD2,MGC43220,MXD2,MXI,bHLHc11
- Gene Description:
- MAX interactor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq
- Other Designations:
- MAX dimerization protein 2,MAX interacting protein 1,MAX-interacting protein 1,Max-related transcription factor,OTTHUMP00000020467,OTTHUMP00000020468,OTTHUMP00000020469
- Related Disease