PDE4D抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PDE4D抗体

PDE4D抗体

商家询价

产品名称： PDE4D抗体

英文名称： PDE4DAntibody

产品编号： XY12918-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 PDE4D抗体Applications

In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications WB Publications 3 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Mouse, recombinant protein
Images
Prev1NextView more validation data
  • 12918-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 12918-1-AP(PDE4D antibody) at dilution of 1:400
  • 12918-1-AP;mouse colon tissueImmunohistochemistry of paraffin-embedded mouse colon tissue slide using 12918-1-AP( PDE4D Antibody) at dilution of 1:100 (under 10x lens).
  • 12918-1-AP;mouse colon tissueImmunohistochemistry of paraffin-embedded mouse colon tissue slide using 12918-1-AP( PDE4D Antibody) at dilution of 1:100 (under 40x lens).
Positive WB detected in Mouse brain tissue, mouse pancreas tissue
Positive IHC detected in Mouse colon tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:50-1:500
 PDE4D抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen PDE4D fusion protein ag3588 Full name Phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
Calculated molecular
weight		 809aa,91 kDa Observed molecular 
weight		 91 kDa
GenBank accession 
number		 BC036319 Gene ID (NCBI) 5144
Gene symbol PDE4D Synonyms DPDE3, HSPDE4D, PDE43, PDE4D, PDE4DN2, STRK1
Background PDE4D抗体

PDE4D(cAMP-specific 3',5'-cyclic phosphodiesterase 4D) is also named as DPDE3, PDE43 and belongs to the cyclic nucleotide phosphodiesterase family and PDE4 subfamily. PDE4D subtype may be of particular importance as an antidepressant target in that it is regulated by repeated treatment with both norepinephrine and serotonin reuptake inhibitors as well as by the PDE4 inhibitor rolipram(PMID:16730340). It has at least 9 isoforms and all 9 PDE4D isoforms are expressed in healthy adult human hippocampus and in hippocampus from a patient with advanced Alzheimer disease(PMID:17353396). PDE4D抗体

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