TLR6 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TLR6 抗体

TLR6 抗体

商家询价

产品名称: TLR6 抗体

英文名称: TLR6 Antibody

产品编号: XY22240-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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 TLR6 抗体Applications

Tested Applications: ELISA, WB
Cited applications WB
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Cited species Human
Positive WB detected in RAW 264.7 cells, HT-1080 cells, human brain tissue, Jurkat cells, mouse thymus tissue
Recommended dilution WB : 1:500-1:5000
 TLR6 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 22240-1-AP;RAW 264.7 cellRAW264.7 cells were subjected to SDS PAGE followed by western blot with 22240-1-AP(TLR6 antibody) at dilution of 1:1000
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information TLR6 抗体
Immunogen: TLR6 fusion protein ag17686 Full Name: Toll-like receptor 6
Caculated Molecular
Weight:
480aa,56 kDa Observed Molecular 
Weight:
95-110 kDa
GenbankNo BC111755 GeneID: 10333
Symbol TLR6 Synonyms CD286, TLR6, toll like receptor 6
Background

TLR6, also known as CD286, belongs to the Toll-like receptor (TLR) family which are important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to human and share structural and functional similarities. TLR6 can form a heterodimer with TLR2. TLR6 and TLR2 both are recruited to the macrophage phagosome, where they recognize peptidoglycan, a Gram-positive pathogen component (PMID: 11095740). TLR6 interacts with CD36, following CD36 stimulation by oxLDL or amyloid-beta 42, and forms a heterodimer with TLR4. The trimeric complex is internalized and triggers inflammatory response. TLR6 抗体

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