FITC标记的味觉受体蛋白家族10亚基5抗体
产品名称： FITC标记的味觉受体蛋白家族10亚基5抗体
英文名称： Anti-OR10A5/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-OR10A5/FITC Conjugated antibody
FITC标记的味觉受体蛋白家族10亚基5抗体
| 产品编号 | bs-11631R-FITC |
| 英文名称 | Anti-OR10A5/FITC |
| 中文名称 | FITC标记的味觉受体蛋白家族10亚基5抗体 |
| 别 名 | HP3; O10A5_HUMAN; Olfactory receptor 10A1; Olfactory receptor 10A5; Olfactory receptor 11-403; Olfactory receptor-like protein JCG6; OR10A1; OR10A5; OR11-403; R10A1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OR10A5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that leads to the perception of smell. While they share a seven transmembrane domain structure with many neurotransmitter and hormone receptors, olfactory receptors are responsible for the recognition and transduction of odorant signals. OR10A2 (olfactory receptor 10A2) and OR10A5 (olfactory receptor 10A5) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family and are encoded by genes that map to human chromosome 11p15.4. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. Function: Odorant receptor (Potential). May be involved in taste perception. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in the tongue. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 144124 Human SwissProt: Q9H207 Human Unigene: 447478 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
嗅觉受体与鼻子中的气味分子相互作用，从而引发神经元反应，导致嗅觉的产生。虽然它们具有七个跨膜结构域，具有许多神经递质和受体，嗅觉受体负责气味信号的识别和转导。O10A2（嗅觉受体10A2）和Or10A5（嗅觉受体10A5）是属于G-蛋白偶联受体1家族的多向膜蛋白，由人类染色体11p154的基因编码。11号染色体含有1400个以上的基因，几乎包含了4%的人类基因组。Jurvl和Lange Nielsen综合征、杰克布森综合征、尼曼匹克病、遗传性血管水肿和Smith-LeMi-Opz综合征与11号染色体上的基因缺陷有关。