FITC标记的血清淀粉样蛋白A抗体
产品名称： FITC标记的血清淀粉样蛋白A抗体
英文名称： Anti-SAA1/Serum Amyloid A/FITC
产品编号： HZ-19359R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SAA1/Serum Amyloid A/FITC Conjugated antibody
FITC标记的血清淀粉样蛋白A抗体
| 英文名称 | Anti-SAA1/Serum Amyloid A/FITC |
| 中文名称 | FITC标记的血清淀粉样蛋白A抗体 |
| 别 名 | amyloid A, serum; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA2; Serum amyloid A protein; serum amyloid A-1 protein; serum amyloid A1; TP53I4; Tumor protein p53 inducible protein 4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SAA1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012] Function: Major acute phase reactant. Apolipoprotein of the HDL complex. Subunit: Homohexamer; dimer of trimers. Can form amyloid fibrils after partial proteolysis; the native, undenatured protein does not form amyloid fibrils (in vitro). Apolipoprotein of the HDL complex. Binds to heparin. Subcellular Location: Secreted. Tissue Specificity: Expressed by the liver; secreted in plasma (at protein level). Post-translational modifications: This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end. DISEASE: Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. Database links: Entrez Gene: 6288 Human Entrez Gene: 20208 Mouse Omim: 104750 Human SwissProt: P0DJI8 Human SwissProt: P05366 Mouse Unigene: 632144 Human Unigene: 148800 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码apolipoproteins的血清淀粉样蛋白A家族成员。编码的蛋白质是一种主要的急性相蛋白，在炎症和组织损伤中高度表达。这种蛋白质在HDL代谢和胆固醇稳态中也起着重要的作用。高水平的这种蛋白与慢性炎症性疾病相关，包括动脉粥样硬化、类风湿性关节炎、阿尔茨海默病和克罗恩病。这种蛋白质也可能是某些肿瘤的潜在生物标志物。交替剪接导致编码同一蛋白质的多个转录变体。这个基因的假基因被发现在第11号染色体上。[ RefSeq，Jun 2012提供]