FITC标记的KIAA1310蛋白抗体
产品名称： FITC标记的KIAA1310蛋白抗体
英文名称： Anti-KIAA1310/FITC
产品编号： HZ-16997R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KIAA1310/FITC Conjugated antibody
FITC标记的KIAA1310蛋白抗体
| 英文名称 | Anti-KIAA1310/FITC |
| 中文名称 | FITC标记的KIAA1310蛋白抗体 |
| 别 名 | K1310_HUMAN; Kiaa1310; Serum inhibited-related protein; Testis development protein PRTD; Uncharacterized protein KIAA1310. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 96kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1310 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The FLJ10081 gene product has been provisionally designated FLJ10081 pending further characterization Function: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. Subunit: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1. Subcellular Location: Nucleus Database links: Entrez Gene: 55683 Human SwissProt: Q9P2N6 Human Unigene: 516341 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
人类第二大染色体2由2.37亿个编码1400多个基因的碱基组成，约占人类基因组的8%。许多遗传疾病与2号染色体上的基因有关。丑角鳞癣，一种罕见的病态皮肤畸形，与ABCA12基因突变有关。脂类代谢紊乱是与ABCG5和ABCG8相关的。ALSTR综合征是一种极为罕见的隐性遗传性疾病，其原因在于ALMS1基因的突变。有趣的是，2号染色体含有看起来是残留的第二着丝粒和残留的端粒，这证实了人类2号染色体是今天在猿类身上看到的两个祖先染色体古代融合的结果。FLJ1008基因产物已暂时指定为FLJ1008，有待进一步鉴定。