FITC标记的内皮素-1抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的内皮素-1抗体

FITC标记的内皮素-1抗体

商家询价

产品名称: FITC标记的内皮素-1抗体

英文名称: Anti-Big endothelin-1/FITC

产品编号: HZ-0188R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-Big endothelin-1/FITC Conjugated antibody 

FITC标记的内皮素-1抗体

 

英文名称 Anti-Big endothelin-1/FITC
中文名称 FITC标记的内皮素-1抗体
别    名 EDN1_HUMAN; Big endothelin 1; EDN 1; EDN1; EDN1 protein; Endothelin1; Endothelin 1; Endothelin-1; ET 1; ET1; OTTHUMP00000039245; PPET1; Preproendothelin 1; Preproendothelin1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Big endothelin-1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Function:
Endothelins are endothelium-derived vasoconstrictor peptides.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Similarity:
Belongs to the endothelin/sarafotoxin family.

Database links:

Entrez Gene: 1906 Human

Entrez Gene: 13614 Mouse

Entrez Gene: 24323 Rat

Omim: 131240 Human

SwissProt: P05305 Human

SwissProt: P22387 Mouse

SwissProt: P22388 Rat

Unigene: 511899 Human

Unigene: 713645 Human

Unigene: 10918 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

内皮素(Endothelin,ET)是一种强的血管收缩剂,分为ET-1,ET-2,ET-3 三种,ET-1主要在内皮细胞中表达,而ET-2和ET-3则主要在神经系统中表达。ET具有广泛的生物学作用。此抗体是ET-1特异性抗体,与ET-2,ET-3无交叉反应

Endothelins(ET)在血管和非血管平滑肌中显示出强有力的收缩活性。该家族的21氨基酸肽至少存在三种异构体-ET-1、ET-2和ET-3,并且产生于内皮细胞和上皮细胞。ET可以介导细胞和组织的生物学效应,并已证明与肺、肾、心脏和肝脏中的ET受体结合。内皮素1在肺、胎盘干绒毛血管和培养的胎盘血管平滑肌细胞中均有表达。