GRAMD4抗体-抗体-抗体-生物在线

GRAMD4抗体

商家询价

产品名称： GRAMD4抗体

英文名称： GRAMD4Antibody

产品编号： XY 24299-1

产品价格： null

产品产地：中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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产品详情

GRAMD4抗体

Applications

Tested Applications:	ELISA, WB
Specificity Reaction:	Human; Other species are not tested.Please decide the specificity by homology
Positive WB detected in	PC-3 cells
Recommended dilution	WB : 1:200-1:1000

GRAMD4抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence

Images

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PC-3 cells were subjected to SDS PAGE followed by western blot with 24299-1-AP( GRAMD4 Antibody) at dilution of 1:300

Product Information

Source:	Rabbit	Purify:	Antigen affinity purification
IsoType:	IgG	Storage:	PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.

Immunogen Information GRAMD4抗体

Immunogen:	GRAMD4 fusion protein ag19140	Full Name:	GRAM domain containing 4
Caculated Molecular Weight:	578aa,66 kDa	Observed Molecular Weight:	66, 140 kDa
GenbankNo	BC129837	GeneID:	23151
Symbol	GRAMD4	Synonyms	DA59H18.1, Death inducing protein, DIP, dJ439F8.1, GRAM domain containing 4, GRAMD4, KIAA0767

Background

GRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly(ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies. GRAMD4抗体

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