FITC标记的配对盒基因9抗体
产品名称： FITC标记的配对盒基因9抗体
英文名称： Anti-PAX9/FITC
产品编号： HZ-1102R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-PAX9/FITC Conjugated antibody
FITC标记的配对盒基因9抗体
| 英文名称 | Anti-PAX9/FITC |
| 中文名称 | FITC标记的配对盒基因9抗体 |
| 别 名 | Paired box 9; Paired box gene 9; Paired box homeotic gene 9; Paired box protein 9; Paired box protein Pax 9; Paired box protein Pax9; Paired domain gene 9; PAX 9; PAX9_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 信号转导 细胞凋亡 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAX9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: PAX9 is a member of the paired box (PAX) family of transcription factors. Proteins in this family typically contain a paired box domain, a paired type homeodomain and an octapeptide sequence. They are important during fetal development and have also been implicated in cancer growth. The exact role of PAX9 is unclear, but it is thought to be involved in development of various organs, skeletal tissue and stratified squamous epithelia. Mutations in PAX9 have also been implicated in oligodontia, a type of tooth agenesis which is a common developmental anomoly in humans. Function: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs (By similarity). Subunit: Interacts with KDM5B. Subcellular Location: Nucleus. DISEASE: ooth agenesis selective 3 (STHAG3) [MIM:604625]: A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth). Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Contains 1 paired domain. Database links: Entrez Gene: 5083 Human Entrez Gene: 18511 Mouse Entrez Gene: 362741 Rat Omim: 167416 Human SwissProt: P55771 Human SwissProt: P47242 Mouse SwissProt: Q2L4T2 Rat Unigene: 132576 Human Unigene: 609574 Human Unigene: 5035 Mouse Unigene: 82416 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 同源结构域蛋白（Homeodomain Proteins） PAX9属于转录抑制因子PAXs的一种。在胚胎发育和肿瘤生长中起关键作用。其突变和某些肿瘤的发病有关。< |
PAX9是成对盒（PAX）转录因子家族的成员。该家族中的蛋白质通常包含成对的盒结构域、配对型同源结构域和八肽序列。它们在胎儿发育过程中很重要，也与癌症的生长有关。
PAX9的确切作用尚不清楚，但它被认为参与各种器官、骨骼组织和分层鳞状上皮的发育。PAX9的突变也与少突症有关，少突症是一种常见的牙齿发育异常。