FITC标记的透明质酸及粘蛋白2抗体
产品名称： FITC标记的透明质酸及粘蛋白2抗体
英文名称： Anti-HAPLN2/FITC
产品编号： HZ-11051R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HAPLN2/FITC Conjugated antibody
FITC标记的透明质酸及粘蛋白2抗体
| 产品编号 | bs-11051R-FITC |
| 英文名称 | Anti-HAPLN2/FITC |
| 中文名称 | FITC标记的透明质酸及粘蛋白2抗体 |
| 别 名 | Brain link protein 1; Bral1; Hapln2; HPLN2_HUMAN; Hyaluronan and proteoglycan link protein 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HAPLN2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern. Function: Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid. Subcellular Location: Secreted, extracellular space, extracellular matrix (By similarity). Tissue Specificity: Expressed only in adult brain. Similarity: Belongs to the HAPLN family. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Contains 2 Link domains. Database links: UniProtKB/Swiss-Prot: Q9GZV7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
HaPLN2是由人基因HaPLN2编码的340个氨基酸。HaPLN2属于HAPLN家族，含有一个免疫球蛋白（Ig）样、V型结构域和两个连接结构域。HaPLN2介导Vistin V2与透明质酸的牢固结合。HaPLN2被认为在中枢神经系统（CNS）中透明质酸相关基质的形成中起着关键性的作用，这有利于神经元的传导和一般的结构稳定。HaPLN2也可能参与细胞外基质的形成，有助于神经外膜网，并有助于了解这些细胞外基质的功能作用。HaPLN2存在于中脑和后脑的多个核中，位于神经束周围网状结构中。