GSTM4 (Human) Recombinant Protein (P01)
产品名称： GSTM4 (Human) Recombinant Protein (P01)
英文名称： GSTM4 (Human) Recombinant Protein (P01)
产品编号： H00002948-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GSTM4 full-length ORF ( AAH15513, 1 a.a. - 218 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
- Theoretical MW (kDa):
- 49.72
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2948
- GeneBank Accession#:
- BC015513
- Protein Accession#:
- AAH15513
- Gene Name:
- GSTM4
- Gene Alias:
- GSTM4-4,GTM4,MGC131945,MGC9247
- Gene Description:
- glutathione S-transferase mu 4
- Omim ID:
- 138333
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq
- Other Designations:
- GST class-mu 4,GTS-Mu2,OTTHUMP00000013356,OTTHUMP00000013358,S-(hydroxyalkyl)glutathione lyase M4,glutathione S-alkyltransferase M4,glutathione S-aralkyltransferase M4,glutathione S-aryltransferase M4,glutathione S-transferase M4
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Breast Neoplasms
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cognition
- Coronary Artery Disease
- Coronary Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hearing Loss
- Hypertension
- Kidney Failure, Chronic
- Lung Neoplasms
- Neoplasms, Second Primary
- Prenatal Exposure Delayed Effects