NDEL1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
NDEL1 抗体

NDEL1 抗体

商家询价

产品名称： NDEL1 抗体

英文名称： NDEL1 Antibody

产品编号： XY17262-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 NDEL1 抗体Applications

Tested Applications: ELISA, WB, IP
Cited applications IF, WB
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Cited species Mouse
Positive WB detected in Human brain tissue, HepG2 cells
Positive IP detected in HepG2 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:1000
 NDEL1 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 17262-1-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 17262-1-AP(NDEL1 antibody) at dilution of 1:500
  • 17262-1-AP;HepG2 cellsIP Result of anti-NDEL1 (IP:17262-1-AP, 4ug; Detection:17262-1-AP 1:300) with HepG2 cells lysate 2400ug.
Product Information NDEL1 抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: NDEL1 fusion protein ag10975 Full Name: NudE nuclear distribution gene E homolog (A. nidulans)-like 1
Caculated Molecular
Weight:		 345aa,38 kDa,41 kDa Observed Molecular 
Weight:		 38-42kd
GenbankNo BC026101 GeneID: 81565
Symbol NDEL1 Synonyms DKFZp451M0318, EOPA, MITAP1, Mitosin associated protein 1, NDEL1, NUDEL, Protein Nudel
Background

Nuclear distribution factor E-homolog 1 (NDE1), NDE-like 1 (NDEL1), and Lissencephaly 1 (LIS1) together involve in essential neurodevelopmental processes, including neuronal precursor proliferation and differentiation, neurite outgrowth, and neuronal migration. All three bind directly to Disrupted in Schizophrenia 1 (DISC1), a scaffold protein critical to neuronal proliferation, integration, migration, and synaptic function within the developing and adult brain.[PMID: 18469341] Nuclear distribution element-like 1 (NDEL1) was firstly identified as a regulator of the cytoskeleton in microtubule and intermediate fliament dynamics and microtubule-based transport [PMID:21948775]. It is required for organization of the cellular microtubule array and microtubule anchoring at the centrosome, which is in part by targeting the microtubule severing protein KATNA1 to the centrosome[PMID:15728732]. NDEL1 抗体

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