FITC标记的粒细胞-巨噬细胞克隆刺激因子抗体
产品名称: FITC标记的粒细胞-巨噬细胞克隆刺激因子抗体
英文名称: Anti-GM-CSF/FITC
产品编号: HZ-3790R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-GM-CSF/FITC Conjugated antibody
FITC标记的粒细胞-巨噬细胞克隆刺激因子抗体
英文名称 | Anti-GM-CSF/FITC |
中文名称 | FITC标记的粒细胞-巨噬细胞克隆刺激因子抗体 |
别 名 | Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 免疫学 信号转导 趋化因子 细胞表面分子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 14kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GM-CSF (102-111aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]. Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Subunit: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits. Subcellular Location: Secreted. Similarity: Belongs to the GM-CSF family. Database links: Entrez Gene: 1437 Human Omim: 138960 Human SwissProt: P04141 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GM-CSF是血管内皮细胞、单核细胞和成纤维细胞合成的糖蛋白。能促进中性粒细胞成熟;刺激成熟的粒细胞从骨髓释出;增强中性粒细胞趋化及吞噬功能 |
由该基因编码的蛋白质是控制粒细胞和巨噬细胞的产生、分化和功能的细胞因子。蛋白质的活性形式在胞外被发现为同型二聚体。该基因已定位于5q31染色体区域的一组相关基因,这已知与5q综合征和急性髓性白血病间质缺失有关。集群中的其他基因包括编码白细胞介素4, 5和13的那些基因。[ RefSeq,JUL 2008 ]提供。