Recombinant human SGK3 protein
重组人丝氨酸蛋白激酶Sgk3蛋白
| 英文名称 | Recombinant human SGK3 protein |
| 中文名称 | 重组人丝氨酸蛋白激酶Sgk3蛋白 |
| 别 名 | CISK; Cytokine independent survival kinase; Serine/threonine protein kinase Sgk3; Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid regulated kinase 3; Serum/glucocorticoid regulated kinase family member 3; Serum/glucocorticoid regulated kinase like; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like; SGK 2; SGK 3; SGK2; Sgk3; SGK3_HUMAN; SGKL. |
| 理论分子量 | 44.8kDa |
| 检测分子量 | 42 kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | >0.5 mg/ml |
| 序 列 | 160-496/496 |
| 纯 度 | >90% by SDSD-PAGE |
| 内毒素 | Not analyzed |
| 活性 | No tested |
| 标签 | N-His Tag |
| 缓 冲 液 | PBS pH7.5 |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Serine/threonine-protein kinase Sgk3 (SGK3), also designated serum/glucocorticoid regulated kinase 3, belongs to the Ser/Thr protein kinase family of proteins. The serum- and glucocorticoid-regulated kinase proteins are closely related to the Akt protein family. SGK1, a homolog of SGK3, activates ion channels, in particular potassium (K+) channels. SGK2 and SGK3 have been found to also be involved in this activation process, making all three of these proteins important regulators for cell proliferation, epithelial transport and neuromuscular excitability. SGK3 acts as a mediator of IL-3 dependent survival signals in the cell. It localizes to the early endosome and in vesicle-like structures. SGK3 is a widely expressed protein, but it is primarily detected in kidney, liver, pancreas, brain and heart. Phosphorylation of SGK3 at residue Ser 486 leads to an increase in SGK3 activation |
本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用！